Nanocluster-antibody-drug conjugates (NADC) as an intravesical precision theranostic agent for interstitial cystitis
Zhijun Lin, Wanyan Wang, Dingxin Liu, Qiwei Liu, Chenyixin Wang, Zhifeng Xu, Zhiming Wu, Xiangfu Zhou, Xiaodong Zhang, Yong Huang, Qi Zhao, Jiang Yang
This paper develops a nanocluster-antibody-drug conjugate (NADC) for interstitial cystitis, showing it targets NGF-overexpressing bladder lesions and reduces inflammation in rat models.
bioRxiv · Apr 20, 2024 · PreprintMicrobiology