Author

Xiangmeng Kong

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:gene regulatory network inference· 3 Assay:whole-genome sequencing· 3 Research Focus:differential expression· 2 Research Focus:GWAS / association mapping· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Jason J. LiuiD· 3 shared Mark GersteiniD· 3 shared Shantao LiiD· 3 shared Timur R. GaleeviD· 3 shared Bing ReniD· 2 shared David U. GorkiniD· 2 shared Donghoon LeeiD· 2 shared Fábio C. P. NavarroiD· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersGenomics

Jason J. LiuORCID

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Author profile →

4 papers

Recent·Most cited

The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models

Joel S. Rozowsky, Jiahao Gao, Beatrice Borsari, Yucheng Yang, Timur R. Galeev, Gamze Gürsoy, Charles B. Epstein, Kun Xiong, Jinrui Xu, Tianxiao Li, Jason J. Liu, Keyang Yu, Ana Berthel, Zhanlin Chen, Fábio C. P. Navarro, , B Bernstein

The paper introduces the EN-TEx resource, which provides personal epigenomes and variant-impact models across multiple tissues, revealing allele-specific loci and their associations with GWAS loci.

Cell · Mar 1, 2023Peer-reviewedGenomics

An integrative ENCODE resource for cancer genomics

Jing Zhang, Donghoon Lee, Vineet K. Dhiman, Peng Jiang, Jie Xu, Patrick D. McGillivray, Hongbo Yang, Jason J. Liu, William U. Meyerson, Declan Clarke, Mengting Gu, Shantao Li, Shaoke Lou, Jinrui Xu, Lucas Lochovsky, , Mark Gerstein

The paper develops a custom ENCODE annotation for cancer genomics, highlighting TF-RBP interactions and network rewiring during oncogenesis, and validates findings using experimental assays.

Nature Communications · Jul 29, 2020Peer-reviewedGenomics

TopicNet: a framework for measuring transcriptional regulatory network change

Shaoke Lou, Tianxiao Li, Xiangmeng Kong, Jing Zhang, Jason J. Liu, Donghoon Lee, Mark Gerstein

TopicNet measures transcriptional regulatory network change by abstracting gene regulatory topics and quantifying rewiring scores between cellular states, revealing TFs with significant network connectivity changes and their impact on cancer survival.

Bioinformatics · May 9, 2020Peer-reviewedBioinformatics

Multi-platform discovery of haplotype-resolved structural variation in human genomes

Mark Chaisson, Ashley D. Sanders, Xuefang Zhao, Ankit Malhotra, David Porubskỳ, Tobias Rausch, Eugene J. Gardner, Oscar L. Rodriguez, Li Guo, Ryan L. Collins, Xian Fan, Jia Wen, Robert E. Handsaker, Susan Fairley, Zev N. Kronenberg, , Charles Lee

This study identifies a large number of structural variants in human genomes using multiple sequencing technologies and presents them as a gold standard for future studies.

Nature Communications · Apr 16, 2019Peer-reviewedGenomics