Author

Xiaoman Cheng

Sun Yat-sen University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Bo LiniD· 1 shared Chi ZhouiD· 1 shared Jia-Hua He· 1 shared Jian-Hong Peng· 1 shared Jiayi Qin· 1 shared Junzhong LiniD· 1 shared Long YuiD· 1 shared Qingjian OuiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Bo LinORCID

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1 paper

Recent·Most cited

RIPK4 driven by TP53 mutations promotes resistance to redox stress of CRC by phosphorylating MTHFD1

Long Yu, Sha Zhou, Yanbo Xu, Z Zhang, Xiaoman Cheng, Chi Zhou, Weihao Li, Jia-Hua He, Qingjian Ou, Jiayi Qin, Yu-Jing Fang, Jian-Hong Peng, Junzhong Lin, Bo Lin, Zhenlin Hou, Zhizhong Pan

This study identifies RIPK4 as a driver of chemotherapy resistance in CRC through TP53 mutations, enhancing MTHFD1 phosphorylation and NADPH production to reduce ROS and promote metastasis.

bioRxiv · Aug 6, 2024 · PreprintMolecular Biology