Bo Lin

The paper identifies a metabolic adaptation in KRAS-inhibited cancer cells that enables resistance through fatty acid scavenging via ADGRB1-PI3Kγ signaling, and shows targeting this pathway restores sensitivity to KRAS inhibitors.

The paper identifies an inflammatory memory mechanism that disables DDR1 degradation, promoting pancreatic cancer growth by preserving DDR1 stability.

This study compares lysis methods for Candida albicans using the Cellometer X2, finding that high-pH buffers with heat are effective, while SDS and Zymolyase show varying efficiency.

This study identifies RIPK4 as a driver of chemotherapy resistance in CRC through TP53 mutations, enhancing MTHFD1 phosphorylation and NADPH production to reduce ROS and promote metastasis.