Long Yu

The paper shows that glycolytic waves in the cell cortex drive migration and cancer progression by providing ATP for morphological events and correlating with metastatic potential.

This study shows that CFAP77 is essential for connecting axonemal A and B tubules in mammalian sperm, as its loss disrupts the CFAP77-CCDC105-TEX43 complex and impairs sperm motility.

This study identifies RIPK4 as a driver of chemotherapy resistance in CRC through TP53 mutations, enhancing MTHFD1 phosphorylation and NADPH production to reduce ROS and promote metastasis.

The paper conducts a GWAS to identify genetic variants associated with TP53 R249S mutation in HCC linked to AFB1 and HBV, finding three significant SNPs.