Xist Intron 1 Repression by TALE Transcriptional Factor Improves Somatic Cell Reprogamming in Mice
Jindun Zhang, Xuefei Gao, Jian Ping Yang, Xiaoying Fan, Wei Wang, Yanfeng Liang, Lihong Fan, Hongmei Han, Xiaorong Xu, Fuchou Tang, Siqin Bao, Pentao Liu, Xihe Li
The paper shows that a TALE-based repressor targeting Xist intron 1 enhances iPSC generation and SCNT embryo development in mice, without affecting Xist expression.
Stem Cells · Oct 24, 2018Peer-reviewedDevelopmental Biology