Production and functional verification of 8-gene (GGTA1, CMAH, β4GalNT2, hCD46, hCD55, hCD59, hTBM, hCD39)-edited donor pigs for xenotransplantation
Jiaoxiang Wang, Kaixiang Xu, Tao Liu, Heng Zhao, Muhammad Ameen Jamal, Gen Chen, Xiaoying Huo, YANG Chang, JIAO Deling, WEI Taiyun, HanFei Huang, Zhao hongfang, Guo JianXiong, Fengchong Wang, Xiong Zhang, , Hongjiang Wei
The paper edits 8 genes in pigs to reduce immune rejection and tests their effectiveness in xenotransplantation to non-human primates.
Cell Proliferation · Apr 6, 2025Peer-reviewedGenetics