Importance of Glutamine in Synaptic Vesicles Revealed by Functional Studies of SLC6A17 and Its Mutations Pathogenic for Intellectual Disability
Xiaobo Jia, Jiemin Zhu, Xiling Bian, Sulin Liu, Sihan Yu, Wenjun Liang, Lifen Jiang, Renbo Mao, Wenxia Zhang, Yi Rao
This study identifies SLC6A17 as a glutamine transporter in synaptic vesicles, linking its dysfunction to intellectual disability through genetic and biochemical analyses.
eLife · Apr 5, 2023Peer-reviewedNeuroscience