Zhiqiang Li

Evidence suggesting creatine as a new central neurotransmitter: presence in synaptic vesicles, release upon stimulation, effects on cortical neurons and uptake into synaptosomes and synaptic vesicles

The paper investigates creatine as a potential central neurotransmitter by analyzing its presence in synaptic vesicles, release patterns, and effects on neurons.

A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene

This study identifies Dnajb6 as a gene causing sick sinus syndrome through a phenotype-based genetic screen in zebrafish.

Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia

A genome-wide association study of 69,369 schizophrenia cases and 236,642 controls identifies 270 risk loci, prioritizes 130 genes, and links common and rare risk variants to neuronal synaptic biology.

A natural marmoset model of genetic generalized epilepsy.

The paper describes a natural marmoset model of generalized epilepsy, showing genetic predisposition and sensitivity to seizure-inducing agents.

Comparative genetic architectures of schizophrenia in East Asian and European populations

This study identifies schizophrenia genetic associations in East Asian and European populations, finding similar genetic effects across ancestries but highlighting challenges in polygenic risk prediction across groups.