Deletion of Pax1 scoliosis-associated regulatory elements leads to a female-biased tail abnormality
Aki Ushiki, Rory R. Sheng, Yichi Zhang, Jingjing Zhao, Mai Nobuhara, Elizabeth Murray, Xin Ruan, Jonathan J. Rios, Carol A. Wise, Nadav Ahituv
The paper identifies a female-biased tail abnormality caused by deletion of Pax1 regulatory elements in mice, linking it to estrogen signaling and AIS susceptibility.
Cell Reports · Mar 1, 2024Peer-reviewedGenetics