Yichi Zhang

AFP-R: An Open Resource Dedicated to Antifreeze Proteins

AFP-R provides a database and predictor for antifreeze proteins, offering curated data and a machine-learning model for AFP identification.

Functional characterization of bat limb regulatory elements

The paper identifies key regulatory elements in bat limb development by comparing bat and mouse genomic datasets and swapping enhancer sequences to observe phenotypic changes.

Taxonomy-free fecal microbiome profiles enable robust prediction of immunotherapy response and toxicity in melanoma

This study identifies microbiome-derived protein biomarkers for predicting immunotherapy response and toxicity in melanoma without relying on taxonomic classification.

Deletion of Pax1 scoliosis-associated regulatory elements leads to a female-biased tail abnormality

The paper identifies a female-biased tail abnormality caused by deletion of Pax1 regulatory elements in mice, linking it to estrogen signaling and AIS susceptibility.

Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis

This study identifies a genetic variant in COL11A1 associated with adolescent idiopathic scoliosis and proposes a molecular model involving Pax1, Col11a1, and Mmp3 in spinal chondrocytes.

Piezo1 potentially mediates inflammation in balloon-inflated rat brain and its bidirectional mechanosensitivity

This study shows that Piezo1 mediates neuroinflammation in a rat model of hematoma compression, with its expression and inflammatory response affected by balloon deflation time.