A glutamatergic DRN-VTA pathway for neuropathic pain and comorbid depression-like behavior modulation
Xin-Yue Wang, Wen-Bin Jia, Xiang Xu, Rui Chen, Liangbiao Wang, Xiao-Jing Su, Pengfei Xu, Xiao-Qing Liu, Jie Wen, Yuanyuan Liu, Zhi Zhang, Xinfeng Liu, Yan Zhang
This study identifies a glutamatergic pathway from VGluT3DRN to DAVTA that modulates neuropathic pain and depression-like behavior through DA release in the NAcMed.
bioRxiv · Mar 22, 2023 · PreprintNeuroscience