Author

Zhi Zhang

University of Science and Technology of ChinaORCID 0000-0002-4205-3181Unclaimed ORCID profile · follow to get notified of new preprints

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Zhi Zhang2 papers · Beijing Normal University

Biology Disciplines

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Neuroscience· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Alberto M. PereiraiD· 1 shared Andries KalsbeekiD· 1 shared Anhui Wang· 1 shared Cheng Wu· 1 shared Chun‐Xia YiiD· 1 shared Dirk Jan StenversiD· 1 shared Ewout FoppeniD· 1 shared Felipe Corrêa‐da‐SilvaiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

Alberto M. PereiraORCID

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3 papers

Recent·Most cited

Limited microglial metabolic improvement with time-restricted feeding in diet-induced obesity

Han Jiao, Jarne Jermei, Xian Liang, Hendrik J.P. van der Zande, Frank Vrieling, Valentina Sophia Rumanova, Milan Dorscheidt, Felipe Corrêa‐da‐Silva, Anhui Wang, Ewout Foppen, Alberto M. Pereira, Dirk Jan Stenvers, TieMin LIU, Kimberly Bonger, Rinke Stienstra, , Chun‐Xia Yi

This study examines how time-restricted feeding affects microglial immunometabolism in obese rats, finding that TRF during the active phase reduces fat mass and alters microglial transcriptome rhythmicity, but does not reverse HFD-induced metabolic inflexibility.

Cell Reports · Oct 1, 2025Peer-reviewedImmunology

A glutamatergic DRN-VTA pathway for neuropathic pain and comorbid depression-like behavior modulation

Xin-Yue Wang, Wen-Bin Jia, Xiang Xu, Rui Chen, Liangbiao Wang, Xiao-Jing Su, Pengfei Xu, Xiao-Qing Liu, Jie Wen, Yuanyuan Liu, Zhi Zhang, Xinfeng Liu, Yan Zhang

This study identifies a glutamatergic pathway from VGluT3DRN to DAVTA that modulates neuropathic pain and depression-like behavior through DA release in the NAcMed.

bioRxiv · Mar 22, 2023 · PreprintNeuroscience

Single-cell RNA sequencing uncovers the excitatory/inhibitory synaptic unbalance in the retrosplenial cortex after peripheral nerve injury

Jinghua Wang, Cheng Wu, Yan‐Na Lian, Ziyue Wang, Jiajun Dong, Qin Wu, Li Liu, Li Sun, Wei Chen, Wenjuan Chen, Zhi Zhang, Min Zhuo, Xiang‐Yao Li

The paper uses scRNA-seq to identify cell-type-specific transcriptional changes in the retrosplenial cortex after nerve injury, revealing an excitatory/inhibitory synaptic imbalance linked to pain hypersensitivity.

bioRxiv · Jun 9, 2021 · PreprintNeuroscience