Recognition of Galactose by a Scaffold Protein Recruits a Transcriptional Activator for the GAL Regulon Induction in Candida albicans
Xun Sun, Jing Yu, Cheng Zhu, Xinreng Mo, Qiangqiang Sun, Dandan Yang, Chang Su, Yang Lü
The paper identifies Rep1 as a galactose sensor in Candida albicans that recruits Cga1 to activate GAL gene transcription, revealing a novel regulatory mechanism in fungal metabolism.
eLife · Feb 1, 2023Peer-reviewedMolecular Biology