Incomplete lineage sorting of segmental duplications defines the human chromosome 2 fusion site early during African great ape speciation
Zikun Yang, Lu Zhang, Xinrui Jiang, Xiangyu Yang, Kaiyue Ma, DongAhn Yoo, Yong‐Jie Lu, Shilong Zhang, Jieyi Chen, Yanhong Nie, Xinyan Bian, Junmin Han, Lianting Fu, Juan Zhang, Mario Ventura, , Yafei Mao
The paper identifies three ancient segmental duplications at the human chromosome 2 fusion site, showing their differential distribution due to incomplete lineage sorting and their regulatory impact on gene expression.
Cell Genomics · Dec 2, 2025Peer-reviewedEvolutionary Biology