Single-Cell Analysis Reveals Cryptic Prophage Protease LfgB Protects Escherichia coli During Oxidative Stress by Cleaving Antitoxin MqsA
Laura Fernández-García, Xinyu Gao, Michael E. Battisti, Joy Kirigo, Rodolfo García‐Contreras, María Tomás, Yunxue Guo, Xiaoxue Wang, Thomas Keith Wood
The paper uses single-cell analysis to show that the MqsR/MqsA TA system in E. coli protects against oxidative stress via the cryptic prophage protease LfgB, which degrades MqsA to activate stress response genes.
bioRxiv · Sep 23, 2023 · PreprintMolecular Biology