María Tomás

This study identifies 34 phage tail-like bacteriocins (PTLBs) in Pseudomonas aeruginosa genomes, with some showing strong antimicrobial activity against bacterial infections.

The paper identifies PinR, a serine recombinase in E. coli, which inverts prophage DNA to block T2 phage infection by creating a protein that prevents phage receptor binding.

This study develops and tests phage therapy medical products (PTMPs) against carbapenem-resistant Klebsiella pneumoniae ST512 strains, showing partial efficacy and the need for antibiotic combination.

The paper develops a LAMP-CRISPR-Cas13a technique to detect bacterial anti-phage defence systems and assesses the role of quorum sensing in phage resistance.

The paper identifies 12 new Pf-like phages in P. aeruginosa clinical isolates and links their presence to resistance against phage infection through novel anti-phage defence systems.

The paper shows toxin/antitoxin systems induce persister cells to inhibit phage, working with restriction-modification systems to inactivate phage DNA.

The paper uses single-cell analysis to show that the MqsR/MqsA TA system in E. coli protects against oxidative stress via the cryptic prophage protease LfgB, which degrades MqsA to activate stress response genes.

The paper analyzes 50 temperate bacteriophages from carbapenemase-producing E. coli isolates, classifying them into viral families and identifying functional features and potential plasmid-like properties.