Laura Fernández-García

This study identifies 34 phage tail-like bacteriocins (PTLBs) in Pseudomonas aeruginosa genomes, with some showing strong antimicrobial activity against bacterial infections.

This study develops and tests phage therapy medical products (PTMPs) against carbapenem-resistant Klebsiella pneumoniae ST512 strains, showing partial efficacy and the need for antibiotic combination.

The paper develops a LAMP-CRISPR-Cas13a technique to detect bacterial anti-phage defence systems and assesses the role of quorum sensing in phage resistance.

The paper identifies 12 new Pf-like phages in P. aeruginosa clinical isolates and links their presence to resistance against phage infection through novel anti-phage defence systems.

The paper shows toxin/antitoxin systems induce persister cells to inhibit phage, working with restriction-modification systems to inactivate phage DNA.

The paper uses single-cell analysis to show that the MqsR/MqsA TA system in E. coli protects against oxidative stress via the cryptic prophage protease LfgB, which degrades MqsA to activate stress response genes.

This study shows that CRISPR-Cas in E. coli is active and suppresses cryptic prophages through RNAi, preventing cell death and persister cell resuscitation.

The paper analyzes 50 temperate bacteriophages from carbapenemase-producing E. coli isolates, classifying them into viral families and identifying functional features and potential plasmid-like properties.