Author

Xiukai Chen

University of Pittsburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Ajay Ram Srimath KandadaiD· 1 shared Alay Gandhi· 1 shared Angka Bulbul· 1 shared Anthony W. DeMartinoiD· 1 shared Daniel B. Kim‐ShapiroiD· 1 shared Elmira AlipouriD· 1 shared Hyon S. HwangiD· 1 shared Jacob E. CorrentiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Ajay Ram Srimath KandadaORCID

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1 paper

Recent·Most cited

Engineering a highly selective, hemoprotein-based scavenger as a carbon monoxide poisoning antidote with no hypertensive effect

Matthew R. Dent, Anthony W. DeMartino, Qinzi Xu, Xiukai Chen, Alay Gandhi, Hyon S. Hwang, Kaitlin A. Bocian, Jacob E. Correnti, Youmna Abdelghany, Elmira Alipour, Kamil B. Ucer, Stephen R. Baker, Ajay Ram Srimath Kandada, Angka Bulbul, Daniel B. Kim‐Shapiro, , Mark T. Gladwin

This paper develops a hemoprotein-based CO scavenger that selectively removes CO from hemoglobin, accelerates its clearance, and avoids hypertension compared to hemoglobin-based treatments.

Proceedings of the National Academy of Sciences · Aug 5, 2025Peer-reviewedBiochemistry