Author

Xu Dong

Virginia Tech

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:deep learning· 2 Organism:human· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Hongda JiangiD· 2 shared Junyan WuiD· 2 shared Ruichen RongiD· 2 shared Chen XieiD· 1 shared Eric Z Chen· 1 shared Eric Z. CheniD· 1 shared Jimmy LiniD· 1 shared Jose Santiago Aguilar· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBioinformatics

Hongda JiangORCID

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3 papers

Recent·Most cited

Modeling Western Pacific Amyotrophic Lateral Sclerosis and Parkinsonism dementia Complex with Microglia Containing Cerebral Organoids Derived from Induced Pluripotent Stem Cells

Yiling Hong, Xu Dong, Lawrence Chang, Chen Xie, Mariann Chang, Jose Santiago Aguilar, Jimmy Lin, Juncheng Lin, Qingshun Quinn Li

This paper uses patient-derived iPSC to generate cerebral organoids modeling ALS-PDC, showing BMAA exposure causes microglial M1 polarization and metabolic dysregulation.

iScience · Feb 24, 2023Peer-reviewedNeuroscience

Lesion Attributes Segmentation for Melanoma Detection with Deep Learning

Eric Z. Chen, Xu Dong, Junyan Wu, Hongda Jiang, Xiaoxiao Li, Ruichen Rong

The paper presents two deep learning models for detecting melanoma lesion attributes using dermoscopic images, achieving a Jaccard index of 0.433 on test data.

bioRxiv · Sep 10, 2018 · PreprintBioinformatics

Skin Lesion Segmentation with Improved C-UNet Networks

Hongda Jiang, Ruichen Rong, Junyan Wu, Xiaoxiao Li, Xu Dong, Eric Z Chen

The paper improves the C-UNet network for skin lesion segmentation, achieving an average Jaccard Index of 0.77 on the online validation dataset.

bioRxiv · Aug 1, 2018 · PreprintBioengineering