Author

Lawrence Chang

Western University of Health SciencesORCID 0000-0002-2938-5309Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Chen XieiD· 1 shared Jimmy LiniD· 1 shared Jose Santiago Aguilar· 1 shared Juncheng LiniD· 1 shared Mariann Chang· 1 shared Qingshun Quinn LiiD· 1 shared Xu Dong· 1 shared Yiling HongiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperNeuroscience

Chen XieORCID

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1 paper

Recent·Most cited

NeuroscienceiSciencePeer-reviewedFeb 24, 2023

Modeling Western Pacific Amyotrophic Lateral Sclerosis and Parkinsonism dementia Complex with Microglia Containing Cerebral Organoids Derived from Induced Pluripotent Stem Cells

Yiling Hong, Xu Dong, Lawrence Chang…·Qingshun Quinn Li

This paper uses patient-derived iPSC to generate cerebral organoids modeling ALS-PDC, showing BMAA exposure causes microglial M1 polarization and metabolic dysregulation.

47 citationstop 4%

humanspatial transcriptomics

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