Author

Xueguang Sun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Baoliang Zhu· 1 shared Bo Wang· 1 shared Darany Tan· 1 shared Guo Chen· 1 shared Guoqiang Zhao· 1 shared Haodong Zhu· 1 shared Hefei Li· 1 shared Jian Cui· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBioinformatics

Baoliang Zhu

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2 papers

Recent·Most cited

Multimodal AI for Single cfDNA Profiling and Cancer Screening

Bo Wang, Liyang Song, Hefei Li, Nan Lin, Ying Xin, Xiaowen He, Wenxin Liu, Li Liu, Jian Cui, Xuesong Li, Ying Mei, Qiuting You, Haodong Zhu, Guoqiang Zhao, Guo Chen, , Yingjiang Ye

The paper develops a Transformer-based model called cfAI to profile and detect cancer-derived cfDNA by integrating methylation, fragmentomics, and histone modifications, achieving high sensitivity and specificity in multi-cancer detection.

bioRxiv · Dec 30, 2025 · PreprintBioinformatics

Mirror bisulfite sequencing — a method for single-base resolution of hydroxymethylcytosine

Xueguang Sun, Darany Tan, Tzu Hung Chung, Xi-Yu Jia

The paper introduces a method to detect 5-hydroxymethylcytosine at single-base resolution using mirror bisulfite sequencing and applies it to map 5hmC levels in human tissues.

Analytical Chemistry · Nov 20, 2018Peer-reviewedGenomics