Author

Xuejing Lyu

Xiamen University

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Biology Disciplines

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Bioinformatics· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Hongkun Fang· 1 shared Jing YangiD· 1 shared Jintao GuoiD· 1 shared Jun ReniD· 1 shared Qiyuan LiiD· 1 shared Xiaodong Shi· 1 shared Ying ZhouiD· 1 shared Yudi Hu· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBioinformatics

Hongkun Fang

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1 paper

Recent·Most cited

MGPfactXMBD: A Model-Based Factorization Method for scRNA Data Unveils Bifurcating Transcriptional Modules Underlying Cell Fate Determination

Jun Ren, Ying Zhou, Yudi Hu, Jing Yang, Hongkun Fang, Xuejing Lyu, Jintao Guo, Xiaodong Shi, Qiyuan Li

MGPfactXMBD is a model-based manifold-learning framework for scRNA-seq data that identifies bifurcating transcriptional modules underlying cell fate determination, outperforming existing methods in trajectory inference and biological interpretation.

eLife · Feb 5, 2025Peer-reviewedBioinformatics