Jun Ren

This study benchmarks 14 RNA velocity methods across 17 datasets, finding no single method outperforms all others and highlighting the need for method comparison in analysis.

MGPfactXMBD is a model-based manifold-learning framework for scRNA-seq data that identifies bifurcating transcriptional modules underlying cell fate determination, outperforming existing methods in trajectory inference and biological interpretation.

This study reports a novel SERPINE1-FOSB fusion gene in pseudomyogenic hemangioendothelioma that activates the PI3K-AKT-mTOR pathway and responds to sirolimus treatment.