BioinformaticseLifePeer-reviewed
MGPfactXMBD: A Model-Based Factorization Method for scRNA Data Unveils Bifurcating Transcriptional Modules Underlying Cell Fate Determination
Jun Ren, Ying Zhou, Yudi Hu…·Qiyuan Li
MGPfactXMBD is a model-based manifold-learning framework for scRNA-seq data that identifies bifurcating transcriptional modules underlying cell fate determination, outperforming existing methods in trajectory inference and biological interpretation.