Trajectory inference of epithelial-centered neighborhood profiles reconstructs a pseudo-temporal continuum in idiopathic pulmonary fibrosis
Satoshi Nakamura, Kazuya Tsubouchi, Y Yamamoto, Tomotsugu Takano, Kosei Nakatsuru, Tomoyoshi Takenaka, Mikiko Hashisako, Yoshinao Oda, Isamu Okamoto
The paper reconstructs a pseudo-temporal continuum of fibrotic remodeling in IPF by analyzing epithelial-centered neighborhood profiles across spatially heterogeneous lung tissue.
bioRxiv · Jun 18, 2026 · PreprintBioinformatics