Kazuya Tsubouchi

This study shows that IL-1β suppresses IFN-γ-induced MHC-I surface expression in NSCLC cells through SQSTM1-dependent autophagy, revealing a post-transcriptional regulatory mechanism.

The paper reconstructs a pseudo-temporal continuum of fibrotic remodeling in IPF by analyzing epithelial-centered neighborhood profiles across spatially heterogeneous lung tissue.

This study shows that Gremlin, an inhibitor of BMP, promotes AT2 cell proliferation and differentiation into AT1s during lung injury, facilitating alveolar repair.