Author

Mikiko Hashisako

Kyushu UniversityORCID 0000-0001-5245-7342Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:spatial transcriptomics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Isamu OkamotoiD· 2 shared Satoshi NakamuraiD· 2 shared Yoshinao OdaiD· 2 shared Daisuke ShibaharaiD· 1 shared Eiji IwamaiD· 1 shared Kazuya TsubouchiiD· 1 shared Keita Nakatomi· 1 shared Kentaro TanakaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioinformatics

Isamu OkamotoORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 18, 2026

Trajectory inference of epithelial-centered neighborhood profiles reconstructs a pseudo-temporal continuum in idiopathic pulmonary fibrosis

Satoshi Nakamura, Kazuya Tsubouchi, Y Yamamoto…·Isamu Okamoto

The paper reconstructs a pseudo-temporal continuum of fibrotic remodeling in IPF by analyzing epithelial-centered neighborhood profiles across spatially heterogeneous lung tissue.

DOI 10.64898/2026.06.15.732243

humanspatial transcriptomics

𝕏 PostBluesky

Cancer BiologybioRxivPreprintFeb 10, 2025

Spatial dynamics of the tumor microenvironment associated with emerging resistance to targeted therapy in EGFR-mutated non-small cell lung cancer

Satoshi Nakamura, Daisuke Shibahara, Kentaro Tanaka…·Isamu Okamoto

The paper uses spatial transcriptomics to analyze pre- and post-treatment tumor samples, identifying fibroblast activation and tumor heterogeneity as factors in early EGFR-TKI resistance.

1 citation

humanspatial transcriptomics

𝕏 PostBluesky