Engineered model of t(7;12)(q36;p13) AML recapitulates patient-specific features and gene expression profiles
D. Ragusa, Y. Ciciro, C. Federico, S. Saccone, F. Bruno, R. Saeedi, C. Sisu, C. Pina, A. Sala, S. Tosi
This study creates a t(7;12) AML model in K562 cells that mirrors patient-specific gene expression and features, aiding in understanding disease mechanisms.
bioRxiv · Jun 14, 2022Cancer Biology