Author

Y. H. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

S. D. Schoville· 3 shared D. J. Hawthorne· 2 shared Z. P. Cohen· 2 shared B. D. Weibel· 1 shared B. Pelissie· 1 shared C. Corrigan· 1 shared C. M. Hawrylowicz· 1 shared C. Wang· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersEvolutionary Biology

S. D. Schoville

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Author profile →

5 papers

Recent·Most cited

TNFAIP8 is a novel phosphoinositide-binding inhibitory regulator of Rho GTPases that promotes cancer cell migration

M. Lin, H. Sun, S. A. Fayngerts, P. Huangyang, Y. H. Chen

This study identifies TNFAIP8 as a phosphoinositide-binding regulator of Rho GTPases that promotes cancer cell migration by linking inflammation to phosphoinositide signaling.

bioRxiv · Mar 26, 2021 · PreprintCell Biology

Genome resequencing reveals rapid, repeated evolution in the Colorado potato beetle, Leptinotarsa decemlineata

B. Pelissie, Y. H. Chen, Z. P. Cohen, M. S. Crossley, D. Hawthorne, S. D. Schoville

This study uses genome resequencing to show that the Colorado potato beetle evolves insecticide resistance repeatedly through standing genetic variation, not novel mutations or regulatory changes.

bioRxiv · Feb 9, 2021 · PreprintEvolutionary Biology

Elevated rates of positive selection drive the evolution of pestiferousness in the Colorado potato beetle (Leptinotarsa decemlineata, Say)

Z. P. Cohen, K. Brevik, Y. H. Chen, D. J. Hawthorne, B. D. Weibel, S. D. Schoville

This study identifies genes under positive selection in the Colorado potato beetle linked to pestiferous traits like detoxification and chemosensation.

bioRxiv · Dec 10, 2019Evolutionary Biology

Effects of vitamin D on inflammatory and oxidative stress responses of human bronchial epithelial cells exposed to particulate matter.

P. E. Pfeffer, H. Lu, E. H. Mann, Y. H. Chen, T.-R. Ho, D. J. Cousins, C. Corrigan, F. J. Kelly, I. S. Mudway, C. M. Hawrylowicz

This study investigates how vitamin D affects inflammatory and oxidative stress responses in human bronchial epithelial cells exposed to particulate matter, finding it enhances antioxidant pathways and modulates immune responses.

bioRxiv · Jun 20, 2018Immunology

Origin of pest lineages of the Colorado potato beetle, Leptinotarsa decemlineata

V. Izzo, Y. H. Chen, S. D. Schoville, C. Wang, D. J. Hawthorne

This study investigates the origin of pest lineages of the Colorado potato beetle by analyzing genetic diversity across populations in Mexico and the U.S., finding that pest lineages originated from native U.S. populations rather than Mexican ones.

bioRxiv · Jun 28, 2017Evolutionary Biology