Y. Komatsu

A Novel Method to Visualize Active Small GTPases Unveils Distinct Sites of Sar1 Activation During Collagen Secretion.

The paper introduces SAIYAN, a method to detect small GTPase activation, revealing Sar1 activation at ER exit sites and ERGIC during collagen secretion.

Mitotic ER exit site dissociation and reassembly is regulated by TANGO1 phosphorylation status

The paper shows that TANGO1 phosphorylation by CK1 during mitosis disrupts its interaction with Sec16, causing ER exit site dissociation, while a phosphatase PP1 regulates this process.