Chlamydia-driven ISG15 expression dampens the immune response of epithelial cells independently of ISGylation
Yongzheng Wu, Chang Liu, Chongfa Tang, Béatrice Niragire, Y. Levy-Zauberman, Cindy Adapen, Thomas Vernay, Juliette Hugueny, Véronique Baud, Agathe Subtil
This study shows that ISG15 expression in epithelial cells infected with Chlamydia trachomatis reduces inflammation and bacterial load without requiring ISGylation.
mBio · Sep 30, 2024Peer-reviewedMicrobiology