Author

Y. Mely

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Assay:fluorescence / live-cell microscopy· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1

Frequent Co-Authors

J. Godet· 3 shared H. Manko· 2 shared I. J. Schalk· 2 shared V. Gasser· 2 shared A. Brandel· 1 shared A. Forster· 1 shared D. Dujardin· 1 shared E. Boutant· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersBiophysics

J. Godet

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

PvdL Orchestrates the Assembly of the Nonribosomal Peptide Synthetases Involved in Pyoverdine Biosynthesis in Pseudomonas aeruginosa.

H. Manko, T. Steffan, V. Gasser, Y. Mely, I. J. Schalk, J. Godet

This study uses single-molecule microscopy to show that PvdL is localized at the inner membrane and co-localizes with other NRPSs, suggesting it orchestrates their assembly in pyoverdine biosynthesis.

bioRxiv · Dec 12, 2023 · PreprintMicrobiology

Advancing Spectrally-Resolved Single Molecule Localization Microscopy using Deep Learning

H. Manko, Y. Mely, J. Godet

This paper introduces srUnet, a deep learning method that improves spectral and spatial precision in srSMLM by compensating for signal loss, achieving performance close to conventional SMLM.

bioRxiv · Jul 29, 2022 · PreprintBiophysics

The bacterial lectin LecA from P. aeruginosa alters membrane organization by dispersing ordered domains

T. Sych, R. Omidvar, R. Ostmann, T. Schubert, A. Brandel, L. Richert, Y. Mely, J. Madl, W. Roemer

This study investigates how the bacterial lectin LecA from P. aeruginosa alters membrane nanodomain organization by dispersing ordered domains using supported lipid bilayers.

bioRxiv · Apr 17, 2022Biophysics

The two zinc fingers in the nucleocapsid domain of the HIV-1 Gag precursor are equivalent for the interaction with the genomic RNA in the cytoplasm, but not for the recruitment of the complexes at the plasma membrane

S. Bernacchi, E. Boutant, J. Bonzi, H. Anton, M. B. Nasim, R. Cathagne, E. Real, D. Dujardin, P. Carl, P. Didier, J.-C. Paillart, R. Marquet, Y. Mely, H. de Rocquigny

This study investigates the role of zinc fingers in HIV-1 Gag's interaction with genomic RNA and their contribution to complex recruitment at the plasma membrane.

Biophysical Journal · Jul 1, 2020Peer-reviewedBiophysics

Supra-molecular organization of the pyoverdine bio-synthetic pathway in Pseudomonas aeruginosa.

V. Gasser, M. Malrieu, A. Forster, Y. Mely, I. J. Schalk, J. Godet

The paper uses single-molecule tracking and FRET-FLIM to show PvdA interacts with NRPS in Pseudomonas aeruginosa, forming organized multi-enzyme complexes called siderosomes.

bioRxiv · Apr 5, 2019Biophysics