Y. Mohamud

Cleavage of 14-3-3ϵ by the enteroviral 3C protease dampens RIG-I mediated antiviral signaling

This study shows that enteroviral 3C protease cleaves 14-3-3ε, disrupting RIG-I signaling and promoting viral infection.

The papain-like protease of coronaviruses cleaves ULK1 to disrupt host autophagy

This study identifies SARS-CoV-2 papain-like protease (PLpro) as a novel substrate of ULK1, demonstrating its role in disrupting host autophagy to promote viral replication.