Author

Y. Muftuoglu

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Assay:structural biology· 1

Frequent Co-Authors

A. F. M. Pinto· 1 shared A. Manglik· 1 shared A. Saghatelian· 1 shared B. Faust· 1 shared C. B. Billesboelle· 1 shared I. Singh· 1 shared K. Zhang· 1 shared N. Hoppe· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

A. F. M. Pinto

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1 paper

Recent·Most cited

Autoantibody and hormone activation of the thyrotropin G protein-coupled receptor

B. Faust, I. Singh, K. Zhang, N. Hoppe, A. F. M. Pinto, Y. Muftuoglu, C. B. Billesboelle, A. Saghatelian, Y. Cheng, A. Manglik

This study determines cryogenic-electron microscopy structures of active and inactive TSHR, revealing how autoantibodies and TSH activate the receptor through similar conformational changes.

bioRxiv · Jan 6, 2022 · PreprintBiochemistry