Author

A. F. M. Pinto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Saghatelian· 2 shared A. E. Sears· 1 shared A. Manglik· 1 shared A. Williams· 1 shared B. Emu· 1 shared B. Faust· 1 shared B. McDonald· 1 shared C. B. Billesboelle· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiochemistry

A. Saghatelian

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Author profile →

3 papers

Recent·Most cited

Autoantibody and hormone activation of the thyrotropin G protein-coupled receptor

B. Faust, I. Singh, K. Zhang, N. Hoppe, A. F. M. Pinto, Y. Muftuoglu, C. B. Billesboelle, A. Saghatelian, Y. Cheng, A. Manglik

This study determines cryogenic-electron microscopy structures of active and inactive TSHR, revealing how autoantibodies and TSH activate the receptor through similar conformational changes.

bioRxiv · Jan 6, 2022 · PreprintBiochemistry

Dissecting lipid contents in the distinct regions of native retinal rod disk membranes

C. L. Sander, A. E. Sears, A. F. M. Pinto, E. H. Choi, S. L. Kahremany, H. G. Jin, S. Suh, E. Pardon, Z. Dong, J. Steyaert, A. Saghatelian, D. Skowronska-Krawczyk, P. D. Kiser, K. Palczewski

The paper analyzes lipid composition differences between center and rim regions of retinal rod disk membranes using co-immunopurification and lipidomic analysis.

bioRxiv · Jan 11, 2021Cell Biology

Oxidized Lipids and CD36-Mediated Lipid Peroxidation in CD8 T Cells Suppress Anti-Tumor Immune Responses

S. Xu, O. Chaudhary, P. Rodriguez-Morales, X. Sun, R. Zappasodi, Z. Xu, A. F. M. Pinto, A. Williams, D. Chen, J. S. Low, Y. Farsakoglu, W. Tang, H. Wang, S. K. Varanasi, B. McDonald, , S. M. Kaech

This study identifies CD36-mediated lipid peroxidation driven by oxidized lipids as a mechanism suppressing anti-tumor CD8 T cell functions in murine tumors.

bioRxiv · Sep 3, 2020Immunology