Structural basis for the specificity of PPM1H phosphatase for Rab GTPases
D. Waschbüsch, K. Berndsen, P. Lis, A. Knebel, Y. P. Lam, D. R. Alessi, A. R. Khan
This paper identifies the structural basis for PPM1H phosphatase specificity for Rab GTPases, showing that a flap domain enables recognition of phosphorylated substrates.
bioRxiv · Feb 17, 2021Biochemistry