Author

A. R. Khan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Bioengineering· 2 Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Organism:human· 3 Assay:imaging· 3 Research Focus:protein folding & dynamics· 2 Research Focus:spatial domain detection· 2 Approach:statistical model· 2 Assay:structural biology· 2

Frequent Co-Authors

J. C. Lau· 3 shared D. R. Alessi· 2 shared Y. Xiao· 2 shared A. Knebel· 1 shared B. Hansen· 1 shared C. Gui· 1 shared D. L. Collins· 1 shared D. M. Kuhn· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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3 shared papersBioengineering

J. C. Lau

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A population-averaged structural connectomic brain atlas of 422 HCP-Aging subjects

Y. Xiao, J. C. Lau, T. M. Peters, A. R. Khan

This paper creates a population-averaged structural connectomic brain atlas from 422 HCP-Aging subjects to provide anatomical and structural connectivity information for neurosurgical planning and neurodegenerative research.

bioRxiv · Jun 1, 2023 · PreprintBioengineering

Detection of local growth patterns in longitudinally imaged low-grade gliomas

C. Gui, J. Kai, A. R. Khan, J. C. Lau, J. F. Megyesi

This study uses deformation-based morphometry to analyze growth patterns in low-grade gliomas, finding expansion around tumor edges and no growth in cores or near obstacles.

bioRxiv · Apr 24, 2022 · PreprintCancer Biology

Structural basis for the specificity of PPM1H phosphatase for Rab GTPases

D. Waschbüsch, K. Berndsen, P. Lis, A. Knebel, Y. P. Lam, D. R. Alessi, A. R. Khan

This paper identifies the structural basis for PPM1H phosphatase specificity for Rab GTPases, showing that a flap domain enables recognition of phosphorylated substrates.

bioRxiv · Feb 17, 2021Biochemistry

Structural basis for Rab8a GTPase recruitment of RILPL2 via LRRK2 phosphorylation of switch 2

A. R. Khan, D. R. Alessi, D. Waschbusch, E. Purlyte, P. Pal, E. McGrath

The paper reports the crystal structure of phospho-Rab8a bound to RILPL2, revealing how LRRK2 phosphorylation enables specific interaction and regulation of ciliogenesis.

bioRxiv · Aug 19, 2019Biochemistry

Bridging micro and macro: accurate registration of the BigBrain dataset with the MNI PD25 and ICBM152 atlases

Y. Xiao, J. C. Lau, T. Anderson, J. DeKraker, D. L. Collins, T. Peters, A. R. Khan

The paper registers the BigBrain atlas with MNI PD25 and ICBM152 atlases to bridge histological and MRI data for neurological research and surgery.

bioRxiv · Jul 9, 2019Bioengineering

Longitudinal, Multiparametric MRI Assessment of repetitive mild TBI in rats

A. R. Khan, B. Hansen, N. K. Iversen, J. L. Olesen, M. Angoa-Perez, D. M. Kuhn, L. Ostergaard, S. N. Jespersen

This study uses longitudinal multiparametric MRI to detect microstructural and metabolic changes in rats with repetitive mild TBI, revealing alterations not visible with conventional imaging.

bioRxiv · Jun 10, 2019 · PreprintNeuroscience