Limited recognition of Mycobacterium tuberculosis-infected macrophages by polyclonal CD4 and CD8 T cells from the lungs of infected mice
Y. Patankar, R. Sutiwisesak, S. Boyce, R. Lai, C. Lindestam Arlehamn, A. Sette, S. M. Behar
The paper assesses T cell recognition of Mtb-infected macrophages in mice and finds that CD4 T cells more effectively recognize these cells than CD8 T cells, with BCG vaccination eliciting such responses.
bioRxiv · Jul 11, 2019Immunology