Human iPSC-derived hypertrophic chondrocytes reveal a mutation-specific unfolded protein response in chondrodysplasias
Y. Pretemer, S. Kawai, M. Watanabe, S. Nagata, M. Nishio, S. Tamaki, C. Alev, Y. Yamanaka, J.-Y. Xue, Z. Wang, K. Fukiage, M. Tsukanaka, T. Futami, S. Ikegawa, J. Toguchida
The paper evaluates mutation-specific unfolded protein response in chondrodysplasias using human iPSC-derived hypertrophic chondrocytes and identifies differential ER stress and gene expression changes.
bioRxiv · May 19, 2020 · PreprintCell Biology