In vitro heterochronic parabiosis identifies pigment epithelium-derived factor as a systemic mediator of rejuvenation by young blood
X. Wang, C. Tazearslan, S. Kim, Q. Guo, D. Contreras, J. Yang, A. D. Hudgins, Y. Suh
This study identifies PEDF as a systemic factor in young blood that rejuvenates cells and tissues, using an in vitro heterochronic parabiosis system.
bioRxiv · May 2, 2024 · PreprintCell Biology