Identifying novel B-cell targets for chronic inflammatory autoimmune disease by screening of chemical probes in a patient-derived cell assay
Y. Sundstrom, M.-M. Shang, S. K. Panda, C. Gronwall, F. Wermeling, I. Gunnarsson, I. E. Lundberg, M. Sundstrom, P.-J. Jakobsson, L. Berg
The paper screens chemical probes in a patient-derived cell assay to identify novel B-cell targets for chronic inflammatory autoimmune diseases, finding inhibitors of bromodomain proteins and histone methyl transferases effective in blocking B-cell function.
bioRxiv · Jan 8, 2020Immunology