Inhibition of Severe Acute Respiratory Syndrome Coronavirus 2 main protease by tafenoquine in vitro
Y. Chen, W.-H. Yang, L.-M. Huang, Y.-C. Wang, C.-S. Yang, Y.-L. Liu, M.-H. Hou, C.-L. Tsai, Y.-Z. Chou, B.-Y. Huang, C.-F. Hung, Y.-L. Hung, J.-S. Chen, Y.-P. Chiang, D.-Y. Cho, , M.-C. Hung
This study identifies tafenoquine as an inhibitor of SARS-CoV-2 main protease, showing it reduces protease activity and inhibits viral infection in vitro.
bioRxiv · Aug 14, 2020 · PreprintBiochemistry