Bioorthogonal Catalytic Microneedles Based on a Cytotoxic PEI Matrix for Synergistic Melanoma Therapy
Qian-He Xu, En-Kui Huang, Ya-Jun Chu, Xiaojun Yao, Pei Nian Liu
This paper develops PPPd-MNs that use PEI's cytotoxicity and Pd catalysis to synergistically treat melanoma, achieving 98% tumor inhibition in mice.
ACS Applied Materials & Interfaces · Jun 30, 2026Peer-reviewedBioengineering