A polyketide-based biosynthetic platform for diols, amino alcohols and hydroxyacids
Qingyun Dan, Yan Chiu, Namil Lee, Jose Henrique Pereira, Behzad Rad, Xixi Zhao, Kai Deng, Yiou Rong, Chunjun Zhan, Yan Chen, Seokjung Cheong, Chenyi Li, Jennifer W. Gin, Andria V. Rodrigues, Trent R. Northen, , Jay D. Keasling
This paper introduces a modular polyketide synthase platform for producing diols, amino alcohols, and hydroxyacids using engineered Streptomyces albus strains.
Nature Catalysis · Feb 11, 2025Peer-reviewedBioengineering