Author

Yankai Jia

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Ran TaoiD· 3 shared Andrew E Jaffe· 2 shared Abhinav NelloreiD· 1 shared Alexis Norris· 1 shared Amanda J. PriceiD· 1 shared Andrew E. JaffeiD· 1 shared Anna Brandtjen· 1 shared Daniel R Weinberger· 1 shared

Activity by Year

2016-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersNeuroscience

Ran TaoORCID

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Author profile →

3 papers

Recent·Most cited

Divergent neuronal DNA methylation patterns across human cortical development: Critical periods and a unique role of CpH methylation

Amanda J. Price, Leonardo Collado‐Torres, Nikolay A. Ivanov, Wei Ting Xia, Emily E. Burke, Joo Heon Shin, Ran Tao, Liang Ma, Yankai Jia, Thomas M. Hyde, Joel E. Kleinman, Daniel R. Weinberger, Andrew E. Jaffe

This study characterizes DNA methylation changes in human neurons across development, identifies distinct methylation patterns, and links them to heritable brain-related phenotypes.

Genome biology · Sep 25, 2019Peer-reviewedNeuroscience

A framework for RNA quality correction in differential expression analysis

Andrew E Jaffe, Ran Tao, Alexis Norris, Marc Kealhofer, Abhinav Nellore, Yankai Jia, Thomas Hyde, Joel Kleinman, Richard Straub, Jeffrey T Leek, Daniel Weinberger

This paper introduces a framework to correct RNA quality effects in differential expression analysis, showing improved replication rates in schizophrenia studies.

bioRxiv · Sep 9, 2016Bioinformatics

Strong Components of Epigenetic Memory in Cultured Human Fibroblasts Related to Site of Origin and Donor Age

Nikolay A Ivanov, Ran Tao, Joshua G Chenoweth, Anna Brandtjen, Michelle I Mighdoll, John D Genova, Ronald D McKay, Yankai Jia, Daniel R Weinberger, Joel E Kleinman, Thomas M Hyde, Andrew E Jaffe

The paper identifies epigenetic memory in cultured human fibroblasts related to their origin and donor age, showing widespread DNA methylation and transcriptome differences.

PLOS Genetics · Feb 25, 2016Peer-reviewedCell Biology