Amanda J. Price

Widespread methylation quantitative trait loci and their role in schizophrenia risk

The paper identifies widespread genetic influences on DNA methylation in the human brain and links schizophrenia GWAS variants to epigenetic changes.

Characterizing the dynamic and functional DNA methylation landscape in the developing human cortex

The paper characterizes dynamic DNA methylation patterns in the prenatal human cortex, identifying loci associated with gene expression, enhancer states, and psychiatric disorder genes.

Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs

The paper uses hiPSC transcriptomics to study neuronal differentiation and maturation across multiple conditions and develops a tool to estimate neuronal maturity.

Divergent neuronal DNA methylation patterns across human cortical development: Critical periods and a unique role of CpH methylation

This study characterizes DNA methylation changes in human neurons across development, identifies distinct methylation patterns, and links them to heritable brain-related phenotypes.

Regional heterogeneity in gene expression, regulation and coherence in hippocampus and dorsolateral prefrontal cortex across development and in schizophrenia

The paper identifies regional differences in gene expression and regulation in hippocampus and dorsolateral prefrontal cortex across development and in schizophrenia using RNA-seq data from 900 samples.

Characterizing the nuclear and cytoplasmic transcriptomes in developing and mature human cortex uncovers new insight into psychiatric disease gene regulation

The paper characterizes nuclear and cytoplasmic transcriptomes in human cortex development and finds increased nuclear retention in mature brain, linked to psychiatric disease gene regulation.