Facilitating mGluR4 activity reverses the long-term deleterious consequences of chronic morphine exposure
Jérôme A. J. Becker, Lucie P. Pellissier, Yannick Corde, Thibaut Laboute, Audrey Léauté, Jorge Gandía, Julie Le Merrer
This study shows that chronic administration of the mGluR4 PAM VU0155041 reverses long-term behavioral deficits in morphine-abstinent mice by restoring gene expression in the nucleus accumbens.
Neuropsychopharmacology · Dec 21, 2020Peer-reviewedNeuroscience