Selective GSK3α Inhibition Promotes Self-Renewal Across Different Stem Cell States
Duo Wang, Xiukun Wang, Shuling Wang, Kai‐Xuan Shi, Safia Malki, Yanpui Chan, Joshua J. Feng, Jiaqi Tang, Xi Xian Chen, Daniel B. McKim, Chao Zhang, Guang Hu, Qi-Long Ying
This paper shows that selective GSK3 inhibition with BRD0705 supports self-renewal of mouse stem cells and enables co-culture of naive and primed stem cells while preserving their identities.
bioRxiv · May 16, 2025 · PreprintCell Biology