Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation
Ali Akbari, Alison R. Barton, Steven Gazal, Zheng Li, Mohammadreza Kariminejad, Annabel Perry, Yating Zeng, Alissa Mittnik, Nick J. Patterson, Matthew Mah, Xiang Zhou, Alkes L. Price, Eric S. Lander, Ron Pinhasi, Nadin Rohland, , David Reich
This paper detects widespread directional selection in ancient DNA data, identifying 347 genome-wide significant loci and linking them to traits like body fat, skin color, and cognitive performance.
bioRxiv · Sep 14, 2024 · PreprintEvolutionary Biology